目前分類:I.H.C (86)

瀏覽方式: 標題列表 簡短摘要
  • Dec 20 Sun 1998 23:21
  • L26

L26, CD20

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Lambda light chain

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  • Dec 20 Sun 1998 21:28
  • LCA

LCA, Leucocyte common antigen, CD45

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  • Dec 19 Sat 1998 23:34
  • Mart-1

Mart-1, Melan-A, A103

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  • Dec 19 Sat 1998 22:39
  • MITF

MITF, Microphthalmia transcription factor
Interpretation: nuclear immunostaining
Uses: diagnosis of angiomyolipoma (AJSP 2001;25:65), melanoma and other melanogenic tumors

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  • Dec 19 Sat 1998 21:48
  • MOC31

MOC31, 
Distinguishing hepatocellular carcinoma (HCC) from metastatic adenocarcinoma (MA) and cholangiocarcinoma (CC)  (Mod Pathol. 2000 Jul;13(7):773-8)

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  • Dec 19 Sat 1998 20:52
  • MPO

MPO, Myeloperoxidase
Enzyme cytochemistry for myeloperoxidase (not immunohistochemistry) is the most sensitive and specific stain for myeloid leukemias and granulocytic sarcoma
Stains neutrophils strongly (diffuse granular pattern), other granulocytes variably
Positive staining (enzyme cytochemistry): neutrophils, eosinophils, monocytes (variable), AML-M1, M2, microgranular M3
Positive staining (immunohistochemistry): granulocytic sarcoma

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Myogenin
Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
Sensitive and specific for rhabdomyosarcoma
Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle, AJSP 2001;25:1150
Interpretation: nuclear immunostaining

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Neurofilament

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  • Dec 18 Fri 1998 22:24
  • NSE

NSE, Neuron specific enolase


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  • Dec 17 Thu 1998 23:28
  • OPD4

OPD4, CD45RO

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  • Dec 16 Wed 1998 23:31
  • p16

p16

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  • Dec 16 Wed 1998 22:39
  • p53

p53


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  • Dec 16 Wed 1998 21:44
  • p63

p63

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  • Dec 16 Wed 1998 20:48
  • PLAP

PLAP, Placental Alkaline Phosphatase
Positive staining (normal): some infantile germ cells until age 1
Positive staining (disease): most germ cell tumors, particularly seminomas; also breast, lung, ovarian carcinomas (some)

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  • Dec 16 Wed 1998 19:52
  • PR

Progesterone receptor

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  • Dec 16 Wed 1998 18:55
  • PSA

PSA, Prostate specific antigen

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  • Dec 15 Tue 1998 23:57
  • S100

S100

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Synaptophysin
Transmembrane glycoprotein isolated from neuronal presynaptic vesicles
Specific but not sensitive for neuroendocrine tumors; more sensitive in well differentiated tumors
Granular cytoplasmic pattern in small cell carcinoma reflects neurosecretory granules
Positive staining (normal): neuronal cells, neuroendocrine cells

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  • Dec 14 Mon 1998 23:17
  • TdT

TdT, Terminal deoxynucleotidyl transferase
Terminal deoxynucleotidyl transferase also called terminal transferase
Nuclear DNA polymerase in thymic and small number of bone marrow cortical lymphocytes
Catalyzes addition of deoxynucleotides to 3' OH ends of oligonucleotides or polydeoxynucleotides
Used during immunoglobulin and T cell receptor rearrangement

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