目前分類:I.H.C (86)
- Dec 20 Sun 1998 23:21
L26
L26, CD20
- Dec 20 Sun 1998 22:26
Lambda light chain
Lambda light chain
- Dec 20 Sun 1998 21:28
LCA
LCA, Leucocyte common antigen, CD45
- Dec 19 Sat 1998 23:34
Mart-1
Mart-1, Melan-A, A103
- Dec 19 Sat 1998 22:39
MITF
MITF, Microphthalmia transcription factor
Interpretation: nuclear immunostaining
Uses: diagnosis of angiomyolipoma (AJSP 2001;25:65), melanoma and other melanogenic tumors
Interpretation: nuclear immunostaining
Uses: diagnosis of angiomyolipoma (AJSP 2001;25:65), melanoma and other melanogenic tumors
- Dec 19 Sat 1998 21:48
MOC31
MOC31,
Distinguishing hepatocellular carcinoma (HCC) from metastatic adenocarcinoma (MA) and cholangiocarcinoma (CC) (Mod Pathol. 2000 Jul;13(7):773-8)
Distinguishing hepatocellular carcinoma (HCC) from metastatic adenocarcinoma (MA) and cholangiocarcinoma (CC) (Mod Pathol. 2000 Jul;13(7):773-8)
- Dec 19 Sat 1998 20:52
MPO
MPO, Myeloperoxidase
Enzyme cytochemistry for myeloperoxidase (not immunohistochemistry) is the most sensitive and specific stain for myeloid leukemias and granulocytic sarcoma
Stains neutrophils strongly (diffuse granular pattern), other granulocytes variably
Positive staining (enzyme cytochemistry): neutrophils, eosinophils, monocytes (variable), AML-M1, M2, microgranular M3
Positive staining (immunohistochemistry): granulocytic sarcoma
Enzyme cytochemistry for myeloperoxidase (not immunohistochemistry) is the most sensitive and specific stain for myeloid leukemias and granulocytic sarcoma
Stains neutrophils strongly (diffuse granular pattern), other granulocytes variably
Positive staining (enzyme cytochemistry): neutrophils, eosinophils, monocytes (variable), AML-M1, M2, microgranular M3
Positive staining (immunohistochemistry): granulocytic sarcoma
- Dec 19 Sat 1998 19:59
Myogenin
Myogenin
Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
Sensitive and specific for rhabdomyosarcoma
Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle, AJSP 2001;25:1150
Interpretation: nuclear immunostaining
Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation
Sensitive and specific for rhabdomyosarcoma
Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle, AJSP 2001;25:1150
Interpretation: nuclear immunostaining
- Dec 18 Fri 1998 23:22
Neurofilament
Neurofilament
- Dec 18 Fri 1998 22:24
NSE
NSE, Neuron specific enolase
- Dec 17 Thu 1998 23:28
OPD4
OPD4, CD45RO
- Dec 16 Wed 1998 23:31
p16
p16
- Dec 16 Wed 1998 22:39
p53
p53
- Dec 16 Wed 1998 21:44
p63
p63
- Dec 16 Wed 1998 20:48
PLAP
PLAP, Placental Alkaline Phosphatase
Positive staining (normal): some infantile germ cells until age 1
Positive staining (disease): most germ cell tumors, particularly seminomas; also breast, lung, ovarian carcinomas (some)
Positive staining (normal): some infantile germ cells until age 1
Positive staining (disease): most germ cell tumors, particularly seminomas; also breast, lung, ovarian carcinomas (some)
- Dec 16 Wed 1998 19:52
PR
Progesterone receptor
- Dec 16 Wed 1998 18:55
PSA
PSA, Prostate specific antigen
- Dec 15 Tue 1998 23:57
S100
S100
- Dec 15 Tue 1998 22:03
Synaptophysin
Synaptophysin
Transmembrane glycoprotein isolated from neuronal presynaptic vesicles
Specific but not sensitive for neuroendocrine tumors; more sensitive in well differentiated tumors
Granular cytoplasmic pattern in small cell carcinoma reflects neurosecretory granules
Positive staining (normal): neuronal cells, neuroendocrine cells
Transmembrane glycoprotein isolated from neuronal presynaptic vesicles
Specific but not sensitive for neuroendocrine tumors; more sensitive in well differentiated tumors
Granular cytoplasmic pattern in small cell carcinoma reflects neurosecretory granules
Positive staining (normal): neuronal cells, neuroendocrine cells
- Dec 14 Mon 1998 23:17
TdT
TdT, Terminal deoxynucleotidyl transferase
Terminal deoxynucleotidyl transferase also called terminal transferase
Nuclear DNA polymerase in thymic and small number of bone marrow cortical lymphocytes
Catalyzes addition of deoxynucleotides to 3' OH ends of oligonucleotides or polydeoxynucleotides
Used during immunoglobulin and T cell receptor rearrangement
Terminal deoxynucleotidyl transferase also called terminal transferase
Nuclear DNA polymerase in thymic and small number of bone marrow cortical lymphocytes
Catalyzes addition of deoxynucleotides to 3' OH ends of oligonucleotides or polydeoxynucleotides
Used during immunoglobulin and T cell receptor rearrangement