cne21th

Papillary hyperplasia

Seen in untreated autoimmune hyperthyroidism (Graves disease), congenital errors of thyroid metabolism, and hyperfunctioning foci in goitrous glands.
Toxic nodular goiter, the changes are similar but the lesion tends to be focal.

Papillary Hyperplasia in Follicular Nodule
Well-circumscribed solitary thyroid nodules may show a microscopic appearance of papillary growth.

Papillary Carcinoma of the Thyroid

Occur at any age and rarely has been diagnosed as a congenital tumor.
Most in the third and fifth decades .
Women are affected more than men in ratios of 2:1 to 4:1 .
Etiologic factors for papillary carcinoma are not well established.