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    Nuclear Grade of Renal Cell Carcinoma

Grade 1

tumors had small, round nuclei with inconspicuous nucleoli visible
only at x400 magnification

Grade 2

tumors contained round to slightly irregular nuclei with mildly
enlarged nucleoli visible at x200

Grade 3

tumors had round to irregular nuclei with prominent nucleoli
visible at x100

Grade 4

tumors contained enlarged pleomorphic or giant cells

 

RCC grade 1

Grade 1 tumor with small, round nuclei and
inconspicuous nucleoli (H&E, x400).

RCC grade 2

Grade 2 tumor with round to slightly irregular nuclei
with mildly enlarged nucleoli (H&E, x400).

RCC grade 3

Grade 3 tumor with round to irregular nuclei with
prominent nucleoli (H&E, x400).

RCC grade 4

Grade 4 tumor with enlarged pleomorphic cells
(H&E, x400).

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