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 Elston and Ellis grading system

Feature

score   

Tubule and gland formation

 

(more than 75%)

(10%~75%)

(Less than 10%)

1

2

3

Nuclear pleomorphism

 

Uniform or regular, small nuclei

Moderate degree of variation in nuclear size and shape and occasional nucleoli

Marked variation in nuclear size and shape and those containing bizarre nuclei, often with irregular chromatin distribution and one or more prominent nucleoli

1

2

3

 

Mitotic count  a diameter of 0.59 mm and an area of 0.274 mm2

 

0–9 mitotic figures per 10 hpf

10-19 mitotic figures per 10 hpf

> 20 mitotic figures per 10 hpf

1

2

3

Grade 1 (well differentiated): 3–5 points
Grade 2 (moderately differentiated): 6–7 points
Grade 3 (poorly differentiated): 8–9 points

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